DANIEL L. MOTOLA MD, PhD
Gastroenterology and Hepatology

Specialist in the treatment of Irritable Bowel Syndrome, Inflammatory Bowel Disease, and Chronic Liver Diseases


Dr. Daniel L. Motola M.D., Ph.D.

Dr. Motola is privileged to be offering Gastroenterology and Hepatology services to patients within and around the city of New York as an associate of Gotham Medical Associates.  He currently sees patients at Gotham's downtown location within the Financial District, located at 123 William Street. The office is just a short walk from the Westfield mall, Fulton and Wall Street Subway lines (2,3,4,5,6, J, Z, A, C) in a vibrant and growing area that is highlighted by the beautiful new Freedom Tower.   

Dr. Motola has expertise in the diagnosis, treatment, and management of all areas within General Gastroenterolgy including the most common conditions such as inflammatory bowel disease, celiac disease, chronic abdominal pain, diarrhea, constipation, gastroesophageal reflux disease, stomach/peptic ulcers, and more.

Furthermore, he provides advanced care for patient's with chronic liver diseases including Hepatitis C, Hepatitis B, Autoimmune hepatitis, PBC, PSC, as well as alcoholic and non-alcoholic fatty liver disease. Dr. Motola is well-versed in the treatment of Hepatitis C and the care of patients with end-stage liver disease.

Patients that require hospital admission are primarily admitted to New York University's Langone Medical Center. Dr. Motola also has affiliations with Lenox Hill Hospital and Mt. Sinai Hospital Beth Israel. These affiliations provide patients with direct access to quality care within top academic medical centers in New York City.

Finally, Dr. Motola is proud to have developed a network of colleagues across the country within several top academic centers (Stanford University, UCLA, Scripps Torrey Pines, John's Hopkins University, University of Mississippi (Jackson), UTSW Medical Center Dallas, and Massachusetts General Hospital). Thus, no medical issue is too complex.


Areas of Practice


Inflammatory Bowel Disease (IBD)

IBD as the name connotes involves inflammation of the gastrointestinal tract. Three forms are recognized. Ulcerative colitis, Crohn's disease, and indeterminate colitis. Dr. Motola will help define your disease and provide optimal treatment strategies that maximize benefits over risks of treatment. Therapy is based on evidence-based medicine and FDA approved treatments. More holisitic approaches are considered with emphasis on dietary triggers of symptoms.


Hepatitis C

Once difficult to treat, now the disease can be cured in as few as 8 weeks. Dr. Motola will help you navigate through the process of obtaining approval for therapy and ensure a positive outcome. Since hepatitis C causes scarring, it will be important to ensure appropriate follow up and screening for liver cancer.

Irritable Bowel Syndrome (IBS)

One in 5 people suffer from IBS characterized by abdominal pain that is associated with changes in bowel pattern. Pain is relieved with bowel movements. Dr. Motola's approach involves identifying triggers of symptoms such as anxiety and dietary intolerance. Success is built on developing a strong doctor-patient relationship. 


Rectal Bleeding

Rectal bleeding requires a thorough evaluation to rule out ominous causes. Benign conditions such as hemorrhoids or anal fissures / tears may be the most common causes. Other causes include proctitis, colon cancer, or diverticular disease.

Celiac Disease

Now common in up to 1% of the population. Symptoms overlap with IBS. Treatment relies on a clear diagnosis and appropriate follow up. Adherence to a gluten free diet is paramount to success


Gastroesophageal Reflux Disease

This disease can lead to swallowing problems and is associated with Barrett's esophagus, a condition that can predispose to esophageal cancer. Caucasian males over the age of 40, who are smokers or obese, have high risk and should be screened for Barrett's esophagus if they have had GERD for many years.


Online Reviews

Read what patients have to say about Dr. Motola. Read more on Zocdoc.com